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Establishment of in vitro Calibration Curve for (60)Co-γ-rays Induced Phospho-53BP1 Foci, Rapid Biodosimetry and Initial Triage, and Comparative Evaluations With γH2AX and Cytogenetic Assays

A rapid and reliable method for biodosimetry of populations exposed to ionizing radiation in the event of an incident or accident is crucial for initial triage and medical attention. DNA-double strand breaks (DSBs) are indicative of radiation exposure, and DSB-repair proteins (53BP1, γH2AX, ATM, etc...

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Detalles Bibliográficos
Autores principales: Chaurasia, Rajesh Kumar, Shirsath, Kapil B., Desai, Utkarsha N., Bhat, Nagesh N., Sapra, B. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393360/
https://www.ncbi.nlm.nih.gov/pubmed/36003625
http://dx.doi.org/10.3389/fpubh.2022.845200