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Dihydromyricetin ameliorates osteogenic differentiation of human aortic valve interstitial cells by targeting c-KIT/interleukin-6 signaling pathway

Aims: Calcific aortic valve disease (CAVD) is a chronic cardiovascular disease with high morbidity that lacks effective pharmacotherapeutics. As a natural flavonoid extracted from Ampelopsis grossedentata, dihydromyricetin (DHM) has been shown to be effective in protecting against atherosclerosis; y...

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Detalles Bibliográficos
Autores principales: Zhang, Shaoshao, Fan, Leilei, Wang, Yongjun, Xu, Jianjun, Shen, Qiang, Xie, Jianhua, Zeng, Zhipeng, Zhou, Tingwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393384/
https://www.ncbi.nlm.nih.gov/pubmed/36003494
http://dx.doi.org/10.3389/fphar.2022.932092