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TGF-β promotes stem-like T cells via enforcing their lymphoid tissue retention

Stem-like CD8(+) T cells sustain the antigen-specific CD8(+) T cell response during chronic antigen exposure. However, the signals that control the maintenance and differentiation of these cells are largely unknown. Here, we demonstrated that TGF-β was essential for the optimal maintenance of these...

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Detalles Bibliográficos
Autores principales: Ma, Chaoyu, Wang, Liwen, Liao, Wei, Liu, Yong, Mishra, Shruti, Li, Guo, Zhang, Xin, Qiu, Yuanzheng, Lu, Qianjin, Zhang, Nu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393408/
https://www.ncbi.nlm.nih.gov/pubmed/35980385
http://dx.doi.org/10.1084/jem.20211538