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Persistent inflammatory pain is linked with anxiety-like behaviors, increased blood corticosterone, and reduced global DNA methylation in the rat amygdala

Chronic pain increases the risk of developing anxiety, with limbic areas being likely neurological substrates. Despite high clinical relevance, little is known about the precise behavioral, hormonal, and brain neuroplastic correlates of anxiety in the context of persistent pain. Previous studies hav...

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Detalles Bibliográficos
Autores principales: Spinieli, Richard L, Cazuza, Rafael Alves, Sales, Amanda Juliana, Carolino, Ruither Oliveira Gomes, Martinez, Diana, Anselmo-Franci, Janete, Tajerian, Maral, Leite-Panissi, Christie RA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393577/
https://www.ncbi.nlm.nih.gov/pubmed/35974687
http://dx.doi.org/10.1177/17448069221121307