Rotenone aggravates PD-like pathology in A53T mutant human α-synuclein transgenic mice in an age-dependent manner

Multiple factors such as genes, environment, and age are involved in developing Parkinson’s disease (PD) pathology. However, how various factors interact to cause PD remains unclear. Here, 3-month and 9-month-old hα-syn(+⁣/−) mice were treated with low-dose rotenone for 2 months to explore the mecha...

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Detalles Bibliográficos
Autores principales: Chen, An-Di, Cao, Jia-Xin, Chen, Hai-Chao, Du, Hong-Li, Xi, Xiao-Xia, Sun, Jing, Yin, Jie, Jing, Yu-Hong, Gao, Li-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393581/
https://www.ncbi.nlm.nih.gov/pubmed/36004003
http://dx.doi.org/10.3389/fnagi.2022.842380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393581/
https://www.ncbi.nlm.nih.gov/pubmed/36004003
http://dx.doi.org/10.3389/fnagi.2022.842380

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