In Vivo Clonal Analysis Reveals Random Monoallelic Expression in Lymphocytes That Traces Back to Hematopoietic Stem Cells

Evaluating the epigenetic landscape in the stem cell compartment at the single-cell level is essential to assess the cells’ heterogeneity and predict their fate. Here, using a genome-wide transcriptomics approach in vivo, we evaluated the allelic expression imbalance in the progeny of single hematop...

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Detalles Bibliográficos
Autores principales: Kubasova, Nadiya, Alves-Pereira, Clara F., Gupta, Saumya, Vinogradova, Svetlana, Gimelbrant, Alexander, Barreto, Vasco M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393635/
https://www.ncbi.nlm.nih.gov/pubmed/36003148
http://dx.doi.org/10.3389/fcell.2022.827774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393635/
https://www.ncbi.nlm.nih.gov/pubmed/36003148
http://dx.doi.org/10.3389/fcell.2022.827774

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