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In Vivo Clonal Analysis Reveals Random Monoallelic Expression in Lymphocytes That Traces Back to Hematopoietic Stem Cells

Evaluating the epigenetic landscape in the stem cell compartment at the single-cell level is essential to assess the cells’ heterogeneity and predict their fate. Here, using a genome-wide transcriptomics approach in vivo, we evaluated the allelic expression imbalance in the progeny of single hematop...

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Detalles Bibliográficos
Autores principales:	Kubasova, Nadiya, Alves-Pereira, Clara F., Gupta, Saumya, Vinogradova, Svetlana, Gimelbrant, Alexander, Barreto, Vasco M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393635/ https://www.ncbi.nlm.nih.gov/pubmed/36003148 http://dx.doi.org/10.3389/fcell.2022.827774

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