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Comparing personalized brain-based and genetic risk scores for major depressive disorder in large population samples of adults and adolescents

BACKGROUND: Major depressive disorder (MDD) is a polygenic disorder associated with brain alterations but until recently, there have been no brain-based metrics to quantify individual-level variation in brain morphology. Here, we evaluated and compared the performance of a new brain-based ‘Regional...

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Detalles Bibliográficos
Autores principales: Thng, Gladi, Shen, Xueyi, Stolicyn, Aleks, Harris, Mathew A., Adams, Mark J., Barbu, Miruna C., Kwong, Alex S. F., Frangou, Sophia, Lawrie, Stephen M., McIntosh, Andrew M., Romaniuk, Liana, Whalley, Heather C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393914/
https://www.ncbi.nlm.nih.gov/pubmed/35899848
http://dx.doi.org/10.1192/j.eurpsy.2022.2301