Full-length dystrophin deficiency leads to contractile and calcium transient defects in human engineered heart tissues

Cardiomyopathy is currently the leading cause of death for patients with Duchenne muscular dystrophy (DMD), a severe neuromuscular disorder affecting young boys. Animal models have provided insight into the mechanisms by which dystrophin protein deficiency causes cardiomyopathy, but there remains a...

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Detalles Bibliográficos
Autores principales: Bremner, Samantha B, Mandrycky, Christian J, Leonard, Andrea, Padgett, Ruby M, Levinson, Alan R, Rehn, Ethan S, Pioner, J Manuel, Sniadecki, Nathan J, Mack, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393922/
https://www.ncbi.nlm.nih.gov/pubmed/36003954
http://dx.doi.org/10.1177/20417314221119628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393922/
https://www.ncbi.nlm.nih.gov/pubmed/36003954
http://dx.doi.org/10.1177/20417314221119628

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