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Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5 (−/−) mice, decreases plasma cholesterol and epididymal fat deposition

We previously showed that Fmo5 (−/−) mice exhibit a lean phenotype and slower metabolic ageing. Their characteristics include lower plasma glucose and cholesterol, greater glucose tolerance and insulin sensitivity, and a reduction in age-related weight gain and whole-body fat deposition. In this pap...

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Detalles Bibliográficos
Autores principales: Veeravalli, Sunil, Varshavi, Dorsa, Scott, Flora H., Varshavi, Dorna, Pullen, Frank S., Veselkov, Kirill, Phillips, Ian R., Everett, Jeremy R., Shephard, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393927/
https://www.ncbi.nlm.nih.gov/pubmed/36003643
http://dx.doi.org/10.3389/fphys.2022.859681