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Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5 (−/−) mice, decreases plasma cholesterol and epididymal fat deposition
We previously showed that Fmo5 (−/−) mice exhibit a lean phenotype and slower metabolic ageing. Their characteristics include lower plasma glucose and cholesterol, greater glucose tolerance and insulin sensitivity, and a reduction in age-related weight gain and whole-body fat deposition. In this pap...
Autores principales: | Veeravalli, Sunil, Varshavi, Dorsa, Scott, Flora H., Varshavi, Dorna, Pullen, Frank S., Veselkov, Kirill, Phillips, Ian R., Everett, Jeremy R., Shephard, Elizabeth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393927/ https://www.ncbi.nlm.nih.gov/pubmed/36003643 http://dx.doi.org/10.3389/fphys.2022.859681 |
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