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Behavioural and molecular characterisation of the Dlg2 haploinsufficiency rat model of genetic risk for psychiatric disorder

Genetic studies implicate disruption to the DLG2 gene in copy number variants as increasing risk for schizophrenia, autism spectrum disorders and intellectual disability. To investigate psychiatric endophenotypes associated with DLG2 haploinsufficiency (and concomitant PSD‐93 protein reduction) a no...

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Detalles Bibliográficos
Autores principales: Waldron, Sophie, Pass, Rachel, Griesius, Simonas, Mellor, Jack R., Robinson, Emma S. J., Thomas, Kerrie L., Wilkinson, Lawrence S., Humby, Trevor, Hall, Jeremy, Dwyer, Dominic M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9393932/
https://www.ncbi.nlm.nih.gov/pubmed/35075790
http://dx.doi.org/10.1111/gbb.12797