Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells

BACKGROUND: Triple-negative breast cancer (TNBC) is associated with aggressiveness and a poor prognosis. Besides surgery, radiotherapy serves as the major treatment modality for TNBC. However, response to radiotherapy is limited in many patients, most likely because of DNA damage response (DDR) sign...

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Detalles Bibliográficos
Autores principales: Khozooei, Shayan, Lettau, Konstanze, Barletta, Francesca, Jost, Tina, Rebholz, Simone, Veerappan, Soundaram, Franz-Wachtel, Mirita, Macek, Boris, Iliakis, George, Distel, Luitpold V., Zips, Daniel, Toulany, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394010/
https://www.ncbi.nlm.nih.gov/pubmed/35989353
http://dx.doi.org/10.1186/s13046-022-02442-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394010/
https://www.ncbi.nlm.nih.gov/pubmed/35989353
http://dx.doi.org/10.1186/s13046-022-02442-x

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