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Lymphatic coagulation and neutrophil extracellular traps in lung-draining lymph nodes of COVID-19 decedents

Clinical manifestations of severe COVID-19 include coagulopathies that are exacerbated by the formation of neutrophil extracellular traps (NETs). Here, we report that pulmonary lymphatic vessels, which traffic neutrophils and other immune cells to the lung-draining lymph node (LDLN), can also be blo...

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Detalles Bibliográficos
Autores principales: MacDonald, Margo E., Weathered, Rachel K., Stewart, Emma C., Magold, Alexandra I., Mukherjee, Anish, Gurbuxani, Sandeep, Smith, Heather, McMullen, Phillip, Mueller, Jeffrey, Husain, Aliya N., Salles, Calixto M., Briquez, Priscilla S., Rouhani, Sherin J., Yu, Jovian, Trujillo, Jonathan, Pyzer, Athalia R., Gajewski, Thomas F., Sperling, Anne I., Kilarski, Witold W., Swartz, Melody A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394105/
https://www.ncbi.nlm.nih.gov/pubmed/35977099
http://dx.doi.org/10.1182/bloodadvances.2022007798