Cargando…

Fbxo45‐mediated NP‐STEP(46) degradation via K6‐linked ubiquitination sustains ERK activity in lung cancer

Lung cancer is one of the most threatening malignant tumors to human health. Epidermal growth factor receptor (EGFR)‐targeted therapy is a common and essential means for the clinical treatment of lung cancer. However, drug resistance has always affected the therapeutic effect and survival rate in no...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Qian, Xu, Ci, Cai, Renjie, An, Weishu, Yuan, Haihua, Xu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394119/
https://www.ncbi.nlm.nih.gov/pubmed/35838331
http://dx.doi.org/10.1002/1878-0261.13290