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Fbxo45‐mediated NP‐STEP(46) degradation via K6‐linked ubiquitination sustains ERK activity in lung cancer
Lung cancer is one of the most threatening malignant tumors to human health. Epidermal growth factor receptor (EGFR)‐targeted therapy is a common and essential means for the clinical treatment of lung cancer. However, drug resistance has always affected the therapeutic effect and survival rate in no...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394119/ https://www.ncbi.nlm.nih.gov/pubmed/35838331 http://dx.doi.org/10.1002/1878-0261.13290 |