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A pipeline for copy number profiling of single circulating tumour cells to assess intrapatient tumour heterogeneity

Intrapatient tumour heterogeneity is likely a major determinant of clinical outcome in cancer patients. To assess heterogeneity in a minimally invasive manner, methods to perform single circulating tumour cell (CTC) genomics at high resolution are necessary. However, due to the rarity of CTCs, devel...

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Detalles Bibliográficos
Autores principales: Deger, Teoman, Mendelaar, Pauline A. J., Kraan, Jaco, Prager‐van der Smissen, Wendy J. C., van der Vlugt‐Daane, Michelle, Bindels, Eric M. J., Sieuwerts, Anieta M., Sleijfer, Stefan, Wilting, Saskia M., Hollestelle, Antoinette, Martens, John W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394233/
https://www.ncbi.nlm.nih.gov/pubmed/34964258
http://dx.doi.org/10.1002/1878-0261.13174