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Potential Pharmacokinetic Effect of Chicken Xenobiotic Receptor Activator on Sulfadiazine: Involvement of P-glycoprotein Induction

Studies on pharmacokinetic drug–drug interactions have highlighted the importance of P-glycoprotein (P-gp) because of its involvement in substrate drug transport. This study aimed to investigate the role of chicken xenobiotic receptor (CXR) in the regulation of P-gp and its influences on pharmacokin...

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Detalles Bibliográficos
Autores principales: Li, Mei, Xu, Ziyong, Lu, Wang, Wang, Liping, Zhang, Yujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394248/
https://www.ncbi.nlm.nih.gov/pubmed/35892397
http://dx.doi.org/10.3390/antibiotics11081005