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Molecular, Subcellular, and Arrhythmogenic Mechanisms in Genetic RyR2 Disease
The ryanodine receptor (RyR2) has a critical role in controlling Ca(2+) release from the sarcoplasmic reticulum (SR) throughout the cardiac cycle. RyR2 protein has multiple functional domains with specific roles, and four of these RyR2 protomers are required to form the quaternary structure that com...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394283/ https://www.ncbi.nlm.nih.gov/pubmed/35892340 http://dx.doi.org/10.3390/biom12081030 |