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Downregulation of miR-210 Promoted Apoptosis of Hippocampal Neurons by Negatively Regulating the TLR4/NF-кB1 Signaling Pathway in a Rat Model of Status Epilepticus

PURPOSE: Status epilepticus (SE) is a life-threatening condition causing brain damage, hippocampal necrosis and apoptosis. This study aimed to determine whether microRNA-210 regulates seizure and apoptosis by targeting the TLR4 /NF-κB1 associated signaling pathway. METHODS: In a pilocarpine-induced...

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Detalles Bibliográficos
Autores principales: Zhou, Qin, Luo, Huanjun, Wang, Xiaowei, Li, Peng, Kong, Haibo, He, Baomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394651/
https://www.ncbi.nlm.nih.gov/pubmed/36003065
http://dx.doi.org/10.2147/NDT.S371950