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Manipulating adrenergic stress receptor signalling to enhance immunosuppression and prolong survival of vascularized composite tissue transplants

BACKGROUND: Vascularized composite tissue allotransplantation (VCA) to replace limbs or faces damaged beyond repair is now possible. The resulting clear benefit to quality of life is a compelling reason to attempt this complex procedure. Unfortunately, the high doses of immunosuppressive drugs requi...

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Detalles Bibliográficos
Autores principales: Kim, Minhyung, Fisher, Daniel T., Bogner, Paul N., Sharma, Umesh, Yu, Han, Skitzki, Joseph J., Repasky, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394753/
https://www.ncbi.nlm.nih.gov/pubmed/35994413
http://dx.doi.org/10.1002/ctm2.996