Stereospecific antiseizure activity in mouse and rat epilepsy models by a pyridinium inhibitor of TNFα/NFκB signaling

Epilepsy affects over 50 million people worldwide and increases the risk of death. An intrinsic state of central inflammation, mainly driven by TNFα/NFκB signaling, may contribute to the refractory nature of some epilepsies. We have therefore hypothesized that inhibitors of this signaling pathway mi...

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Detalles Bibliográficos
Autores principales: Pollard, Bette S., Wen, Zhiwei, Jacobson, Kenneth A., Pollard, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395218/
https://www.ncbi.nlm.nih.gov/pubmed/36003949
http://dx.doi.org/10.1016/j.ejmcr.2022.100065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395218/
https://www.ncbi.nlm.nih.gov/pubmed/36003949
http://dx.doi.org/10.1016/j.ejmcr.2022.100065

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