Snail acetylation by autophagy‐derived acetyl‐coenzyme A promotes invasion and metastasis of KRAS‐LKB1 co‐mutated lung cancer cells

BACKGROUND: Autophagy is elevated in metastatic tumors and is often associated with active epithelial‐to‐mesenchymal transition (EMT). However, the extent to which EMT is dependent on autophagy is largely unknown. This study aimed to identify the mechanisms by which autophagy facilitates EMT. METHOD...

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Detalles Bibliográficos
Autores principales: Han, Jang Hee, Kim, Yong Keon, Kim, Hakhyun, Lee, Jooyoung, Oh, Myung Joon, Kim, Sang Bum, Kim, Minjee, Kim, Kook Hwan, Yoon, Hyun Ju, Lee, Myung‐Shik, Minna, John D., White, Michael A., Kim, Hyun Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395322/
https://www.ncbi.nlm.nih.gov/pubmed/35838183
http://dx.doi.org/10.1002/cac2.12332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395322/
https://www.ncbi.nlm.nih.gov/pubmed/35838183
http://dx.doi.org/10.1002/cac2.12332

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