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Glomerular deposition of galactose-deficient IgA1-containing immune complexes via glomerular endothelial cell injuries
BACKGROUND: Galactose-deficient immunoglobulin A1 (Gd-IgA1) plays a crucial role in the development of IgA nephropathy (IgAN). However, the pathological role of Gd-IgA1-containing immune complexes (ICs) and the mechanism of deposition in the mesangial region remain unclear. METHODS: To examine the d...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395370/ https://www.ncbi.nlm.nih.gov/pubmed/35746884 http://dx.doi.org/10.1093/ndt/gfac204 |