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Glomerular deposition of galactose-deficient IgA1-containing immune complexes via glomerular endothelial cell injuries

BACKGROUND: Galactose-deficient immunoglobulin A1 (Gd-IgA1) plays a crucial role in the development of IgA nephropathy (IgAN). However, the pathological role of Gd-IgA1-containing immune complexes (ICs) and the mechanism of deposition in the mesangial region remain unclear. METHODS: To examine the d...

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Detalles Bibliográficos
Autores principales:	Makita, Yuko, Suzuki, Hitoshi, Nakano, Daisuke, Yanagawa, Hiroyuki, Kano, Toshiki, Novak, Jan, Nishiyama, Akira, Suzuki, Yusuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395370/ https://www.ncbi.nlm.nih.gov/pubmed/35746884 http://dx.doi.org/10.1093/ndt/gfac204

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