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Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology
Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are closely related progressive disorders with no available disease-modifying therapy, neuropathologically characterized by intraneuronal aggregates of misfolded α-synuclein. To explore the role of DNA methylation changes in PD and DLB pat...
Autores principales: | Pihlstrøm, Lasse, Shireby, Gemma, Geut, Hanneke, Henriksen, Sandra Pilar, Rozemuller, Annemieke J. M., Tunold, Jon-Anders, Hannon, Eilis, Francis, Paul, Thomas, Alan J., Love, Seth, Mill, Jonathan, van de Berg, Wilma D. J., Toft, Mathias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395387/ https://www.ncbi.nlm.nih.gov/pubmed/35995800 http://dx.doi.org/10.1038/s41467-022-32619-z |
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