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Label-free chemical imaging of cytochrome P450 activity by Raman microscopy

Although investigating drug modulation of cytochrome P450 (CYP) activity under physiological conditions is crucial in drug development to avoid severe adverse drug reactions, the current evaluation approaches that rely on the destructive and end-point analysis can be misleading due to invasive treat...

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Detalles Bibliográficos
Autores principales: Li, Menglu, Nawa, Yasunori, Ishida, Seiichi, Kanda, Yasunari, Fujita, Satoshi, Fujita, Katsumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395422/
https://www.ncbi.nlm.nih.gov/pubmed/35995965
http://dx.doi.org/10.1038/s42003-022-03713-1