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Label-free chemical imaging of cytochrome P450 activity by Raman microscopy
Although investigating drug modulation of cytochrome P450 (CYP) activity under physiological conditions is crucial in drug development to avoid severe adverse drug reactions, the current evaluation approaches that rely on the destructive and end-point analysis can be misleading due to invasive treat...
Autores principales: | Li, Menglu, Nawa, Yasunori, Ishida, Seiichi, Kanda, Yasunari, Fujita, Satoshi, Fujita, Katsumasa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395422/ https://www.ncbi.nlm.nih.gov/pubmed/35995965 http://dx.doi.org/10.1038/s42003-022-03713-1 |
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