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Astrocyte-Derived TNF-α-Activated Platelets Promote Cerebral Ischemia/Reperfusion Injury by Regulating the RIP1/RIP3/AKT Signaling Pathway

Ischemic stroke is a clinical syndrome caused by the disruption of blood flow into cerebral tissues and is associated with high disability and mortality rates. Studies have established the pathological role of platelets in cerebral ischemia/reperfusion (I/R) injury, although the underlying mechanism...

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Detalles Bibliográficos
Autores principales: Li, Wei, Liu, Dengping, Xu, Jiaqi, Zha, Jun, Wang, Chen, An, Jianzhong, Xie, Zhanli, Qiao, Shigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395439/
https://www.ncbi.nlm.nih.gov/pubmed/35781632
http://dx.doi.org/10.1007/s12035-022-02942-z