Selective GSK3β Inhibition Mediates an Nrf2-Independent Anti-inflammatory Microglial Response

Glycogen synthase kinase 3 (GSK3) is associated with the proinflammatory phenotype of microglia and has been shown to act in concert with nuclear factor kappa B (NF-κB). GSK3 is also a suppressor of nuclear factor erythroid 2-related factor 2 (Nrf2), the principal regulator of redox homeostasis. Agr...

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Detalles Bibliográficos
Autores principales: Yousef, Mohamed H., Salama, Mohamed, El-Fawal, Hassan A. N., Abdelnaser, Anwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395457/
https://www.ncbi.nlm.nih.gov/pubmed/35739410
http://dx.doi.org/10.1007/s12035-022-02923-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395457/
https://www.ncbi.nlm.nih.gov/pubmed/35739410
http://dx.doi.org/10.1007/s12035-022-02923-2

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