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Selective GSK3β Inhibition Mediates an Nrf2-Independent Anti-inflammatory Microglial Response
Glycogen synthase kinase 3 (GSK3) is associated with the proinflammatory phenotype of microglia and has been shown to act in concert with nuclear factor kappa B (NF-κB). GSK3 is also a suppressor of nuclear factor erythroid 2-related factor 2 (Nrf2), the principal regulator of redox homeostasis. Agr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395457/ https://www.ncbi.nlm.nih.gov/pubmed/35739410 http://dx.doi.org/10.1007/s12035-022-02923-2 |