Insulin Deficiency Increases Sirt2 Level in Streptozotocin-Treated Alzheimer’s Disease-Like Mouse Model: Increased Sirt2 Induces Tau Phosphorylation Through ERK Activation

Accumulating evidence suggests that insulin deficiency is a risk factor for Alzheimer’s disease (AD); however, the underlying molecular mechanisms are not completely understood. Here, we investigated the effects of insulin deficiency on AD-like pathologies using an insulin-deficient amyloid-β (Aβ) p...

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Detalles Bibliográficos
Autores principales: Zhou, Chunyu, Jung, Cha-Gyun, Kim, Mi-Jeong, Watanabe, Atsushi, Abdelhamid, Mona, Taslima, Ferdous, Michikawa, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395464/
https://www.ncbi.nlm.nih.gov/pubmed/35701718
http://dx.doi.org/10.1007/s12035-022-02918-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395464/
https://www.ncbi.nlm.nih.gov/pubmed/35701718
http://dx.doi.org/10.1007/s12035-022-02918-z

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