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The miR-183/96/182 cluster is upregulated in glioblastoma carrying EGFR amplification

Glioblastoma (GBM) is one of the most frequent primary brain tumors. Limited therapeutic options and high recurrency rates lead to a dismal prognosis. One frequent, putative driver mutation is the genomic amplification of the oncogenic receptor tyrosine kinase EGFR. Often accompanied by variants lik...

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Detalles Bibliográficos
Autores principales: Schneider, Björn, William, Doreen, Lamp, Nora, Zimpfer, Annette, Henker, Christian, Classen, Carl Friedrich, Erbersdobler, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395473/
https://www.ncbi.nlm.nih.gov/pubmed/35486213
http://dx.doi.org/10.1007/s11010-022-04435-y