Mono-PEGylated thermostable Bacillus caldovelox arginase mutant (BCA-M-PEG20) induces apoptosis, autophagy, cell cycle arrest and growth inhibition in gastric cancer cells

Gastric cancer is one of the most common malignant solid tumors in the world, especially in Asia with high mortality due to a lack of effective treatment. The potential usage of the newly constructed arginine-depleting enzyme—mono-PEGylated Bacillus caldovelox arginase mutant (BCA-M-PEG20), an effec...

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Detalles Bibliográficos
Autores principales: Chung, Sai-Fung, Tam, Suet-Ying, Kim, Chi-Fai, Chong, Hiu-Chi, Lee, Leo Man-Yuen, Leung, Yun-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395487/
https://www.ncbi.nlm.nih.gov/pubmed/35857203
http://dx.doi.org/10.1007/s10637-022-01265-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395487/
https://www.ncbi.nlm.nih.gov/pubmed/35857203
http://dx.doi.org/10.1007/s10637-022-01265-z

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