An open-label, crossover study to compare different formulations and evaluate effect of food on pharmacokinetics of pimitespib in patients with advanced solid tumors

This study compared the bioavailability of two pimitespib formulations (Formulations A and B), evaluated the food effect on Formulation A, and evaluated the safety and efficacy of multiple pimitespib doses in patients with solid tumors. This clinical, pharmacological multicenter study had two cohort...

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Detalles Bibliográficos
Autores principales: Komatsu, Yoshito, Shimokawa, Tsuneo, Akiyoshi, Kohei, Karayama, Masato, Shimomura, Akihiko, Kawamoto, Yasuyuki, Yuki, Satoshi, Tambo, Yuichi, Kasahara, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395490/
https://www.ncbi.nlm.nih.gov/pubmed/35932386
http://dx.doi.org/10.1007/s10637-022-01285-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395490/
https://www.ncbi.nlm.nih.gov/pubmed/35932386
http://dx.doi.org/10.1007/s10637-022-01285-9

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