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iPSCs derived from infertile men carrying complex genetic abnormalities can generate primordial germ-like cells
Despite increasing insight into the genetics of infertility, the developmental disease processes remain unclear due to the lack of adequate experimental models. The advent of induced pluripotent stem cell (iPSC) technology has provided a unique tool for in vitro disease modeling enabling major advan...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395518/ https://www.ncbi.nlm.nih.gov/pubmed/35995809 http://dx.doi.org/10.1038/s41598-022-17337-2 |