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Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models
Considerable evidence supports the release of pathogenic aggregates of the neuronal protein α-Synuclein (αSyn) into the extracellular space. While this release is proposed to instigate the neuron-to-neuron transmission and spread of αSyn pathology in synucleinopathies including Parkinson’s disease,...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395532/ https://www.ncbi.nlm.nih.gov/pubmed/35995799 http://dx.doi.org/10.1038/s41467-022-32625-1 |