Connexin 30 deletion exacerbates cochlear senescence and age-related hearing loss

Pathogenic mutations in the Gjb2 and Gjb6 genes, encoding connexin 26 (Cx26) and connexin 30 (Cx30), respectively, have been linked to the most frequent monogenic hearing impairment, nonsyndromic hearing loss, and deafness DFNB1. It is known that Cx26 plays an important role in auditory development,...

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Detalles Bibliográficos
Autores principales: Paciello, Fabiola, Zorzi, Veronica, Raspa, Marcello, Scavizzi, Ferdinando, Grassi, Claudio, Mammano, Fabio, Fetoni, Anna Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395607/
https://www.ncbi.nlm.nih.gov/pubmed/36016655
http://dx.doi.org/10.3389/fcell.2022.950837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395607/
https://www.ncbi.nlm.nih.gov/pubmed/36016655
http://dx.doi.org/10.3389/fcell.2022.950837

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