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Connexin 30 deletion exacerbates cochlear senescence and age-related hearing loss
Pathogenic mutations in the Gjb2 and Gjb6 genes, encoding connexin 26 (Cx26) and connexin 30 (Cx30), respectively, have been linked to the most frequent monogenic hearing impairment, nonsyndromic hearing loss, and deafness DFNB1. It is known that Cx26 plays an important role in auditory development,...
Autores principales: | Paciello, Fabiola, Zorzi, Veronica, Raspa, Marcello, Scavizzi, Ferdinando, Grassi, Claudio, Mammano, Fabio, Fetoni, Anna Rita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395607/ https://www.ncbi.nlm.nih.gov/pubmed/36016655 http://dx.doi.org/10.3389/fcell.2022.950837 |
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