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First-in-human pilot trial of combined intracoronary and intravenous mesenchymal stem cell therapy in acute myocardial infarction

BACKGROUND: Acute ST-elevation myocardial infarction (STEMI) elicits a robust cardiomyocyte death and inflammatory responses despite timely revascularization. OBJECTIVES: This phase 1, open-label, single-arm, first-in-human study aimed to assess the safety and efficacy of combined intracoronary (IC)...

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Detalles Bibliográficos
Autores principales: Hsiao, Lien-Cheng, Lin, Yen-Nien, Shyu, Woei-Cherng, Ho, Ming, Lu, Chiung-Ray, Chang, Shih-Sheng, Wang, Yu-Chen, Chen, Jan-Yow, Lu, Shang-Yeh, Wu, Mei-Yao, Li, Keng-Yuan, Lin, Yu-Kai, Tseng, Wen-Yih I., Su, Mao-Yuan, Hsu, Chin-Ting, Tsai, Cheng-Kang, Chiu, Lu-Ting, Chen, Chien-Lin, Lin, Cheng-Li, Hu, Kai-Chieh, Cho, Der-Yang, Tsai, Chang-Hai, Chang, Kuan-Cheng, Jeng, Long-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395611/
https://www.ncbi.nlm.nih.gov/pubmed/36017096
http://dx.doi.org/10.3389/fcvm.2022.961920