PLXND1-mediated calcium dyshomeostasis impairs endocardial endothelial autophagy in atrial fibrillation

Left atrial appendage (LAA) thrombus detachment resulting in intracranial embolism is a major complication of atrial fibrillation (AF). Endocardial endothelial cell (EEC) injury leads to thrombosis, whereas autophagy protects against EEC dysfunction. However, the role and underlying mechanisms of au...

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Detalles Bibliográficos
Autores principales: Sun, Mengjia, Chen, Zhen, Song, Yuanbin, Zhang, Bo, Yang, Jie, Tan, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395636/
https://www.ncbi.nlm.nih.gov/pubmed/36017337
http://dx.doi.org/10.3389/fphys.2022.960480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395636/
https://www.ncbi.nlm.nih.gov/pubmed/36017337
http://dx.doi.org/10.3389/fphys.2022.960480

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