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Insulin-like growth factor-1 signaling in the tumor microenvironment: Carcinogenesis, cancer drug resistance, and therapeutic potential

The tumor microenvironment fuels tumorigenesis and induces the development of resistance to anticancer drugs. A growing number of reports support that the tumor microenvironment mediates these deleterious effects partly by overexpressing insulin-like growth factor 1 (IGF-1). IGF-1 is known for its r...

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Detalles Bibliográficos
Autores principales: Nwabo Kamdje, Armel H., Seke Etet, Paul F., Kipanyula, Maulilio J., Vecchio, Lorella, Tagne Simo, Richard, Njamnshi, Alfred K., Lukong, Kiven E., Mimche, Patrice N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395641/
https://www.ncbi.nlm.nih.gov/pubmed/36017326
http://dx.doi.org/10.3389/fendo.2022.927390