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Dexmedetomidine to reduce vasopressor resistance in refractory septic shock: Protocol for a double-blind randomized controlled pilot trial (ADRESS Pilot study)

INTRODUCTION: Refractory septic shock (RSS) is characterized by high vasopressor requirements, as a consequence of vasopressor resistance, which may be caused or enhanced by sympathetic hyperactivation. Experimental models and clinical trials show a reduction in vasopressor requirements and improved...

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Detalles Bibliográficos
Autores principales: Dargent, Auguste, Bourredjem, Abderrahmane, Argaud, Laurent, Levy, Bruno, Fournel, Isabelle, Cransac, Amélie, Badie, Julio, Quintin, Luc, Quenot, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395682/
https://www.ncbi.nlm.nih.gov/pubmed/36017005
http://dx.doi.org/10.3389/fmed.2022.968274