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CaSilico: A versatile CRISPR package for in silico CRISPR RNA designing for Cas12, Cas13, and Cas14

The efficiency of the CRISPR-Cas system is highly dependent on well-designed CRISPR RNA (crRNA). To facilitate the use of various types of CRISPR-Cas systems, there is a need for the development of computational tools to design crRNAs which cover different CRISPR-Cas systems with off-target analysis...

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Detalles Bibliográficos
Autores principales: Asadbeigi, Adnan, Norouzi, Milad, Vafaei Sadi, Mohammad Sadegh, Saffari, Mojtaba, Bakhtiarizadeh, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395711/
https://www.ncbi.nlm.nih.gov/pubmed/36017348
http://dx.doi.org/10.3389/fbioe.2022.957131