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Simvastatin-hydroxyapatite coatings prevent biofilm formation and improve bone formation in implant-associated infections

Implant-associated infections (IAIs) caused by biofilm formation are the most devastating complications of orthopedic surgery. Statins have been commonly and safely used drugs for hypercholesterolemia for many years. Here, we report that simvastatin-hydroxyapatite-coated titanium alloy prevents biof...

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Detalles Bibliográficos
Autores principales: Sun, Tiantong, Huang, Jie, Zhang, Wang, Zheng, Xuanqi, Wang, Hong, Liu, Jing, Leng, Huijie, Yuan, Wanqiong, Song, Chunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395756/
https://www.ncbi.nlm.nih.gov/pubmed/36017072
http://dx.doi.org/10.1016/j.bioactmat.2022.07.028