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A Stable Chemokine Gradient Controls Directional Persistence of Migrating Dendritic Cells

Navigation of dendritic cells (DCs) from the site of infection to lymphoid organs is guided by concentration gradients of CCR7 ligands. How cells interpret chemokine gradients and how they couple directional sensing to polarization and persistent chemotaxis has remained largely elusive. Previous exp...

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Detalles Bibliográficos
Autores principales: Quast, Thomas, Zölzer, Karolin, Guu, Donald, Alvarez, Luis, Küsters, Carsten, Kiermaier, Eva, Kaupp, U. Benjamin, Kolanus, Waldemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395945/
https://www.ncbi.nlm.nih.gov/pubmed/36016652
http://dx.doi.org/10.3389/fcell.2022.943041