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A Stable Chemokine Gradient Controls Directional Persistence of Migrating Dendritic Cells
Navigation of dendritic cells (DCs) from the site of infection to lymphoid organs is guided by concentration gradients of CCR7 ligands. How cells interpret chemokine gradients and how they couple directional sensing to polarization and persistent chemotaxis has remained largely elusive. Previous exp...
Autores principales: | Quast, Thomas, Zölzer, Karolin, Guu, Donald, Alvarez, Luis, Küsters, Carsten, Kiermaier, Eva, Kaupp, U. Benjamin, Kolanus, Waldemar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395945/ https://www.ncbi.nlm.nih.gov/pubmed/36016652 http://dx.doi.org/10.3389/fcell.2022.943041 |
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