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Influence of homoarginine on creatine accumulation and biosynthesis in the mouse

Organisms obtain creatine from their diet or by de novo synthesis via AGAT (L-arginine:glycine amidinotransferase) and GAMT (Guanidinoacetate N-methyltrasferase) in kidney and liver, respectively. AGAT also synthesizes homoarginine (hArg), low levels of which predict poor outcomes in human cardiovas...

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Detalles Bibliográficos
Autores principales: Lygate, Craig A., Lake, Hannah A., McAndrew, Debra J., Neubauer, Stefan, Zervou, Sevasti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395972/
https://www.ncbi.nlm.nih.gov/pubmed/36017222
http://dx.doi.org/10.3389/fnut.2022.969702