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The Biphasic Effect of Retinoic Acid Signaling Pathway on the Biased Differentiation of Atrial-like and Sinoatrial Node-like Cells from hiPSC

BACKGROUND AND OBJECTIVES: Although human-induced pluripotent stem cells (hiPSC) can be efficiently differentiated into cardiomyocytes (CMs), the heterogeneity of the hiPSC-CMs hampers their applications in research and regenerative medicine. Retinoic acid (RA)-mediated signaling pathway has been pr...

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Detalles Bibliográficos
Autores principales: Liu, Feng, Long, Dandan, Huang, Wenjun, Peng, Wanling, Lan, Huan, Zhou, Yafei, Dang, Xitong, Zhou, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396015/
https://www.ncbi.nlm.nih.gov/pubmed/35220280
http://dx.doi.org/10.15283/ijsc21148