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The Emergence of Rod-Cone Cellular Interaction

We studied the origin of rod-derived cone viability factor (RdCVF) during evolution. In mammals, the nucleoredoxin-like 1 gene (NXNL1) produces a truncated thioredoxin-like protein, RdCVF, by intron retention in rod photoreceptors of the retina. This protein prevents the secondary cone degeneration...

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Detalles Bibliográficos
Autores principales: Aït-Ali, Najate, Léveillard, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396122/
https://www.ncbi.nlm.nih.gov/pubmed/36017494
http://dx.doi.org/10.3389/fgene.2022.900849