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Restoring Prohealing/Remodeling-Associated M2a/c Macrophages Using ON101 Accelerates Diabetic Wound Healing

Diabetic wounds exhibit chronic inflammation and delayed tissue proliferation or remodeling, mainly owing to prolonged proinflammatory (M1) macrophage activity and defects in transition to prohealing/proremodeling (M2a/M2c; CD206(+) and/or CD163(+)) macrophages. We found that topical treatment with...

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Detalles Bibliográficos
Autores principales: Lin, Ching-Wen, Chen, Chih-Chiang, Huang, Wen-Yen, Chen, Yen-Yu, Chen, Shiou-Ting, Chou, Hung-Wen, Hung, Chien-Ming, Chen, Wan-Jiun, Lu, Chia-Sing, Nian, Shi-Xin, Chen, Shyi-Gen, Chang, Hsuen-Wen, Chang, Vincent H.S., Liu, Li-Ying, Kuo, Ming-Liang, Chang, Shun-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396230/
https://www.ncbi.nlm.nih.gov/pubmed/36017415
http://dx.doi.org/10.1016/j.xjidi.2022.100138